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Checking Your Skin: Which Mole Changes Matter

A doctor explains which mole changes are worth acting on, how the ABCDE and ugly duckling rules work, and why skin screening programs differ by country.

The short version

  • Change is the signal that matters: a mole that is growing, changing color or shape, bleeding, itching or crusting deserves review, however ordinary it looks.
  • The ABCDE rule and the ugly duckling sign, a spot that looks unlike all your others, catch most concerning lesions.
  • No country runs population-wide skin screening; the standard everywhere is self-examination plus targeted checks for high-risk people.

See a doctor promptly if

These are the signs that change this from something to read about into something to act on.

  • A mole or spot that is changing in size, shape or color over weeks to months
  • A lesion that bleeds, crusts, itches persistently or does not heal within four weeks
  • A new pigmented streak under a nail, or a dark spot on the palm, sole or inside the mouth
  • A firm growing lump in the skin, or a new lump under the arm or in the groin alongside a changing mole

The change is what matters, not the mole. A spot that is growing, shifting color or shape, bleeding, itching or refusing to heal should be looked at by a doctor, even if it seems unremarkable, and a stable mole you have had since childhood almost never needs anything.

Most people have between ten and forty moles. Learning your own pattern is more useful than memorising a checklist.

The two rules worth knowing#

ABCDE is the standard framework for pigmented lesions:

  • Asymmetry. One half does not match the other
  • Border: ragged, notched or blurred edges
  • Colour: more than one color, or uneven distribution
  • Diameter. Larger than about 6 mm, though small melanomas exist
  • Evolving: any change over weeks to months

The ugly duckling sign is arguably more useful in practice. Your moles tend to resemble each other. The one that clearly does not belong in the family deserves attention, even if it passes every ABCDE criterion.

Not every skin cancer is a mole#

Melanoma gets the attention, but basal cell and squamous cell carcinomas are far more common. They look different: a pearly or waxy bump, a flat scaly patch, a persistent sore that scabs and reopens, or a firm growing nodule. A sore that has not healed in four weeks is worth showing someone.

Actinic keratoses, rough, scaly patches on sun-exposed skin in older adults, are pre-cancerous rather than cancerous, and treatable.

Who is at higher risk#

Fair skin that burns easily, red or blond hair, many moles or several atypical ones, a history of blistering sunburn especially in childhood, use of sunbeds, previous skin cancer, a first-degree relative with melanoma, and immunosuppression after transplant or from medication.

Outdoor work is a genuine and under-recognized risk factor. In construction, agriculture, fishing and any role with hours of daily sun, cumulative ultraviolet exposure is an occupational hazard in the same sense as noise or dust, and shade, timing, clothing and sunscreen belong in the risk assessment rather than being left to personal choice.

How to check yourself properly#

Once a month, in good light, after a shower. Work through a fixed order so nothing gets skipped: face and ears, scalp with fingers or a comb, neck, chest and abdomen, both arms including between fingers and under nails, back and shoulders using a mirror or another person, buttocks, legs, and finally soles and between the toes.

Photograph anything you are unsure about, with a ruler or coin for scale, and re-photograph it a month later from the same distance. That comparison answers the question far better than trying to remember.

Where this fits#

Skin checks belong to the same category as blood pressure and screening tests: small, cheap habits that mostly find nothing and occasionally find something early. The fuller guide to health checkups by age explains what else belongs on that list in each decade.

Common questions

Is there a national skin cancer screening program?
Not in the UK, US, EU or Gulf as a population program. Germany offers a national skin check to adults over 35 and Australia has strong public awareness campaigning, but most systems rely on self-examination and referral of suspicious lesions. Regular dermatologist review is offered to high-risk people, such as those with many atypical moles, previous melanoma or a suppressed immune system.
Can people with brown or black skin get melanoma?
Yes, and it is more often diagnosed late. Melanoma in darker skin tends to appear on the palms, soles, under nails and inside the mouth rather than on sun-exposed areas. A new or changing dark streak under a nail or a spot on the sole should be examined.
How often should I check my own skin?
About once a month is enough for most people, and photographs help far more than memory. Use a mirror or ask someone to look at your back and scalp, which is where lesions are most often missed. High-risk people should follow the interval their dermatologist sets.

Sources

  1. NHS: Melanoma skin cancer
  2. NHS: Moles
  3. CDC: Skin cancer
  4. WHO: Ultraviolet radiation
Medically reviewed 17 August 2026How this was written and checked
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